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Myocardial Function of the Setonis Aortic Valve Before and Beyond Valve Replacement

Completed
Conditions
Myocardial Function of the Stenosis Aortic Valve Before and Beyond Valve Replacement
Interventions
Procedure: stenosis aortic valve
Registration Number
NCT03686527
Lead Sponsor
Rennes University Hospital
Brief Summary

Study the consequences on heart muscle of the stenosis aortic valve before and after the replacement procedure, the repercussion on heart. Study the impact on the heart of "sick" valve can affect on "well-being" and prognosis in the year following the surgery.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
277
Inclusion Criteria
  • major patient freely accepting to participate in the study
  • non-opposition signed
  • aortic surface <1cm² or <0.6cm² / m² of indication surgical restraint
  • oriented to short interventional management surgical term
  • LVEF Left ventricular ejection fraction> 50%
  • In the subgroup "MRI-fibrosis", absence of indication for performing MRI
Exclusion Criteria
  • patient under guardianship, curatorship or safeguard of justice
  • minor patient
  • pregnant woman
  • patient with significant polyvalvulopathy for which it is from the start programmed more than aortic valve replacement
  • patient with severe coronary artery disease requiring revascularization
  • allergy to the contrast product

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Echocardiographystenosis aortic valve-
MRI Fibrosisstenosis aortic valve-
Primary Outcome Measures
NameTimeMethod
The primary endpoint is a composite endpoint: all-cause death, cardiovascular hospitalization: cardiac decompensation, atrial fibrillation within 12 months of surgical or percutaneous aortic valve replacement.1 day of inclusion
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

CHU Rennes

🇫🇷

Rennes, Bretagne, France

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