Evaluation of Sertraline effect for Intradialytic Hypotensionin in the dialytic patients that has been referred to dialyse department of Kowsar hospital in Semna
Phase 2
- Conditions
- hypotension.Hypotension, unspecified
- Registration Number
- IRCT2017080625732N23
- Lead Sponsor
- Semnan University of Medical Sciences, Deputy of Research and Technology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Permanent hemodialysis patients for the at least 3 months that in at least 50 percent of their hemodialysis cases in last 3 months, having intra-dialytic hypotension; perform at least 4 hours hemodialysis for 3 times per week; concentration of dialysis fluid: Na: 106 mEq/L, Ca: 5.2 mEq/L, K: 2 mEq/L and mg: 1 mEq/L, Cl: 111.5 mEq/L, HCO3 3.35; fluid dialysis flow: 500 to 600 ml/min; blood flow: 250 to 300 ml/min; antihypertensive agents received during dialysis; available for at least 8 weeks (study time).
Exclusion criteria: Performing hemodialysis in different treatment centers during the time of the study; having mental illness that use the SSRIs drug.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum creatinine level. Timepoint: Before, 12, 24 and 48 hours after intervention. Method of measurement: Exam.;Blood Urea Nitrogen (BUN). Timepoint: Before, 12, 24 and 48 hours after intervention. Method of measurement: Exam.
- Secondary Outcome Measures
Name Time Method