The Effects of Low Dose Sertraline on Blood Pressure in Patients with Hypertension and Panic Disorder: A Pilot Study

Not Applicable

• Conditions: Hypertension related to Panic Disorders; Cardiovascular - Hypertension; Mental Health - Anxiety

• Registration Number: ACTRN12611000293965
• Lead Sponsor: Professor Sean Hood

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-03-21
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Age >40
Male or female
Diagnosed panic disorder/ anxiety disorder
Diagnosed hypertension and on at least one medication for hypertension
Compliant patient with access and availability to attend at least three (3) hospital sessions

Exclusion Criteria

Cardiovascular Instability
Hypotension
Malignancy
Pregnancy or Breast-feeding
Involvement in another clinical trial
Current DSM-IV disorder (apart from Panic Disorder)
Hypersensitivity to, or currently using, any serotonergic medicines
Rural or remote location, or unable to attend for at least three (3) hospital sessions

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome measure is the difference between the change in systolic and diastolic blood pressure in subjects, 14 and 28 days post exposure to low dose Sertraline (50mg final dose)<br><br>To assess this outcome, subjects will have 24hr ambulatory blood pressure monitoring at 0, 14 and 28 days. Blood pressure will be measured every half hour between 9am-9pm, and once every hour between 9pm-9am.[0, 14 and 28 days]

Secondary Outcome Measures

Name	Time	Method
nil[nil]