A pilot study to determine the use of Sertraline in patients with hypertension and anxiety disorder.
Not Applicable
- Conditions
- Health Condition 1: null- Patients with panic disorder and hypertension.
- Registration Number
- CTRI/2015/07/006028
- Lead Sponsor
- King Georges Medical University Department of Geriatric Mental health
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 80
Inclusion Criteria
Diagnosed panic disorder/panic attacks/generalised anxiety disorder who are otherwise suitable for SSRI therapy
-Diagnosed hypertension and on at least one medication for hypertension
-Compliant patient with access and availability to attend at least three (3) additional hospital sessions
Exclusion Criteria
-Cardiovascular Instability, such as history of myocardial infarction, arrhythmias or stroke
-Hypotension
-Currently active malignancy
-Pregnancy or Breast-feeding
-Involvement in another clinical trial
-Current or recent (within 90 days) DSM-IV Major Depressive Disorder.
-Hypersensitivity to, or currently using, any serotonergic medicines, such as tryptophan, tramadol etc
-Contra-indication to serotonergic medicines
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in the scores for panic/anxiety disorder over 4 week period. <br/ ><br> <br/ ><br> <br/ ><br>Timepoint: 12 months <br/ ><br> <br/ ><br> <br/ ><br> <br/ ><br> <br/ ><br>
- Secondary Outcome Measures
Name Time Method Whether Sertraline is successful as adjunctive therapy to standard antihypertensive medications in lowering blood pressure in those with anxiety/panic disorders. <br/ ><br> <br/ ><br> <br/ ><br>Timepoint: 12 months