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The role of the parietal cortex in re-orienting to emotional stimuli: a single-pulse TMS study

Completed
Conditions
fundamenteel onderzoek bij gezonde proefpersonen
NA
Registration Number
NL-OMON42175
Lead Sponsor
Radboud Universiteit Nijmegen
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
18
Inclusion Criteria

Healthy, right-handed participants, between 18*35 years old, with normal or corrected-to-normal vision, normal hearing.

Exclusion Criteria

Exclusion criteria for participation include metal in cranium, epilepsy or family history of epilepsy, history of neurological or psychiatric disorders, medication use (i.e., benzodiazepines, antidepressants andneuroleptica), cardiac pacemaker, pregnancy and electronic hearing devices.

Study & Design

Study Type
Observational invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>Primary study parameters/outcome: A repeated measures ANOVA with Target TMS SOA<br /><br>( 30ms , 60ms , 90ms , 120ms , 150ms , 180ms , 210ms , 240ms , 270ms , 300ms )<br /><br>and Target Type ( threatening ( CS + ) , non -threatening ( CS ) and<br /><br>Cuevalidity (valid, invalid ) as factors will be performed on percentage<br /><br>correct and reaction times. If appropriate, planned comparisons between the<br /><br>conditions will be carried out.</p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Secondary study parameters/outcome: In addition to our primary objective , we<br /><br>will investigate a possible correlation between the degree of<br /><br>anxiety as measured by the VAS and the STAI -T with re - orienting, as indexed<br /><br>by the difference in performance on the CS + target and CS- target.</p><br>
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