Investigating the effect of aspiration with and without Tranexamic acid and Lidocaine injection in Hemophilia patients with knee hemarthrosis
Phase 2
- Conditions
- Hemophilia.Other disorders of blood and blood-forming organs in diseases classified elsewhere
- Registration Number
- IRCT20221216056838N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Hemophilia patients with acute hemarthrosis of the knee joint in the first 24 hours
Exclusion Criteria
Blood clots in the joint
slight bleeding
patient dissatisfaction
joint fluid infection
history of seizures and heart diseases
G6PD
history of DVT
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Range of Motion. Timepoint: 3 Days, aweek later, weekly until complete healing of hemarthrosis. Method of measurement: Using a Protractor.;Type of Hemophilia. Timepoint: Before entering the study. Method of measurement: Using the patient's hemophilia file.;Severity of Hemophilia. Timepoint: Before entering the study. Method of measurement: Using the patient's hemophilia file.;The amount of pain. Timepoint: 3 Days, a week later, weekly until complete healing of hemarthrosis. Method of measurement: Vas score.;Back to Work and School day. Timepoint: Every day until returning to work. Method of measurement: Questionnaire.;Coagulation factor dose. Timepoint: Until receiving the coagulation factor. Method of measurement: Patient's hospitalization file.;How long it takes to end the pain. Timepoint: Every day until the end of the pain. Method of measurement: Questionnaire.
- Secondary Outcome Measures
Name Time Method