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Clinical Trials/NCT05726877
NCT05726877
Recruiting
Not Applicable

Determination of Optimal Positive End-expiratory Pressure in Prone Position During General Anesthesia Using Electrical Impedance Tomography in Pediatric Patient Under 17 Years of Age

Seoul National University Hospital1 site in 1 country51 target enrollmentOctober 17, 2022
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ConditionsVentilation Therapy; Complications

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Ventilation Therapy; Complications
Sponsor
Seoul National University Hospital
Enrollment
51
Locations
1
Primary Endpoint
Optimal positive end-expiratory pressure (PEEP)
Status
Recruiting
Last Updated
3 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

This study aimed to investigate the differences in positive end-expiratory pressure titration in the supine and prone positions by age in pediatric patients under 17 years of age who received general anesthesia and then evaluate the hemodynamic stability.

Registry
clinicaltrials.gov
Start Date
October 17, 2022
End Date
August 31, 2024
Last Updated
3 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • •patients who are scheduled to undergo general anesthesia in the prone position
  • •patients who are in age under 17 years

Exclusion Criteria

  • •had cyanosis or chronic respiratory failure
  • •had respiratory distress syndrome or bronchopulmonary dysplasia
  • •had laryngotracheal diseases
  • •had pulmonary hypertension
  • •receiving oxygen therapy

Outcomes

Primary Outcomes

Optimal positive end-expiratory pressure (PEEP)

Time Frame: 60 minutes after prone positioning

result of decremental PEEP trial

Secondary Outcomes

  • Impedance tidal variation(60 minutes after prone positioning)
  • overdistension or atelectasis(60 minutes after prone positioning)
  • regional ventilation delay(60 minutes after prone positioning)
  • arterial blood gas analysis, if patients has arterial catheter(10 minutes after intubation & 60 minutes after prone positioning)
  • end-expiratory lung impedance(60 minutes after prone positioning)
  • center of ventilation(60 minutes after prone positioning)
  • vital signs(60 minutes after prone positioning)
  • end-expiratory lung volume(60 minutes after prone positioning)
  • regional respiratory system compliance(10 minutes after intubation)

Study Sites (1)

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