Preeclampsia and Circulating Biomarkers

• Conditions: Postpartum CVD Risk in Women With Previous Preeclampsia.

• Registration Number: NCT02136667
• Lead Sponsor: University of Aarhus

Brief Summary

In order to assess circulating biomarkers of cardiovascular risk, we will conduct a 10-year follow-up study comparing 32 exposed (women with a history of pregnancy complicated by preeclampsia) and 32 unexposed (women with a history of uncomplicated pregnancy).

Participants will be recruited from a well-characterised cohort, previously assembled during their pregnancies, at the Department of Obstetrics at Randers Regional Hospital in 2001-2004.

Blood and urine samples, collected during their pregnancies, are stored in a biobank, thus rendering the possibility of longitudinal assessment.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-04
• Status Verified: 2014-05
• Study First Submitted: 2014-05-01
• Study First Submitted QC: 2014-05-08
• Study First Posted: 2014-05-13
• Primary Completion: 2014-12
• Last Update Submitted: 2015-01-05
• Last Update Posted: 2015-01-06
• Study Completion: 2015-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 64

Inclusion Criteria

• Participation in previous study 2001-2005.

Exclusion Criteria

• Current pregnancy or breastfeeding

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Circulating biomarkers of cardiovascular disease 10 years postpartum.	10 years postpartum

Secondary Outcome Measures

Name	Time	Method
Markers of arteriosclerosis and atherosclerosis	10 years postpartum
Circulating biomarkers of cardiovascular disease at baseline pregnancy.	During pregnancy

Trial Locations

Locations (1)

Randers Regional Hospital; 🇩🇰 Randers, Randers NØ, Denmark