Intravenous fluid management in patients with acute hypertensive hemorrhagic stroke: A randomized controlled study

Not Applicable

• Registration Number: CTRI/2021/02/031504
• Lead Sponsor: Institute of Medical Sciences Banaras Hindu University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 17 October 2022

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

All the patients admitted to our hospital with acute hypertensive hemorrhagic stroke (based on clinical and radiological features) within a period of 72hrs from the onset of symptoms and consenting to be part of the study will be included after screening for inclusion and exclusion criteria.

Exclusion Criteria

1.Not willing to participate in the study or no informed consent.

2.Those with GCS less than or equal to 8 at admission.

3.Prepared for or received surgical intervention within 14 days.

4.Patients with co-morbid conditions like cardiac failure, low ejection fraction ( <40%), renal failure with admission serum creatinine more than 2, fluid overload, acute liver failure, liver cirrhosis, cancer under treatment, fever, or any conditions which require more aggressive hydration or blood or blood component transfusion at the time of admission.

5.Patients with sepsis, hypotension, DKA, electrolyte disturbances requiring urgent correction, requiring ICU admission or those with critical illness.

6.Life expectancy or any reasons for follow-up < 3 months.

7.Those who received fluid from other hospital before reaching our hospital.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Proportion of patients with good outcome defined by mRS score of 0-3Timepoint: 3 months

Secondary Outcome Measures

Name	Time	Method
Cardiac failure or evidence of fluid overloadTimepoint: Within 4days;Dehydration during hospital stayTimepoint: Till discharge;Duration of hospital stayTimepoint: At discharge;Worsening of NIHSS score by more than or equal to 3 points unexplained by another causeTimepoint: Within 4days