Prevention and management of neurodegenerative disorders by an Ayurvedic formulatio
Phase 3
- Conditions
- Health Condition 1: G- Mental HealthHealth Condition 2: null- Neurodegenerative disorder
- Registration Number
- CTRI/2014/12/005312
- Lead Sponsor
- Department of Science Technology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Closed to Recruitment of Participants
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Willingness to give informed consent and a deterioration of memory along with at least three of the following five complaints:
1.Poor orientation
2.Poor judgement and problem solving difficulties
3.Trouble in the functioning of community affairs
4. Inability to function independently in home and during hobbies
5. Difficulties in personal care.
Clinical screening for SDAT was done using dementia rating scale-II
Exclusion Criteria
Subjects suffering from any metabolic disease
Established neuropathy or tuberculosis
SDAT patients receiving conventional treatment were excluded from the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improvement in cognitive function particularly memory performance including behavioral abnormalitiesTimepoint: Gradual improvement (3,6,9 and 12 months);Improvement in cognitive function particularly memory performance including behavioral abnormalitiesTimepoint: Gradual improvement (3,6,9 and 12 months);Improvement in cognitive function particularly memory performance including behavioral abnormalitiesTimepoint: Gradual improvement (3,6,9 and 12 months);Improvement in cognitive function particularly memory performance including behavioral abnormalitiesTimepoint: Gradual improvement (3,6,9 and 12 months);Improvement in cognitive function particularly memory performance including behavioral abnormalitiesTimepoint: Gradual improvement (3,6,9 and 12 months)
- Secondary Outcome Measures
Name Time Method Effect on oxidative stress markers, anti-inflammatory activity, homocysteine lowering effects, improvement in attention span, new learning, orientation skill and improvement in sleep patternTimepoint: Gradual improvement (3,6,9 and 12 months)