Efficacy of Levofloxacin- containing versus Clarithromycin -containing Sequential Therapies in Helicobacter pylori Eradicatio
Phase 3
- Conditions
- Gastric ulcer-Duodenal ulcer- Helicobacter pylori [H.pylori] as the cause of diseases classified to other chaptersk25-K26 -Bgastric ulcer or erosion-deudenal ulcer or erosion.
- Registration Number
- IRCT2015030820178N2
- Lead Sponsor
- Iran University of Medical Sciences,Rasoul Akram Hospital,Colorectal Research Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 182
Inclusion Criteria
age more than18 years,patients with endoscopically confirmed peptic ulcer or gastric/duodenal erosions and H. pylori infection documentation by antral biopsy (Giemsa staining) and/or rapid urease test (RUT). exclusion criteria:pregnancy, breast-feeding, previous history of helicobacter pylori eradication,significant underlying diseases such as liver, cardiac, pulmonary or renal diseases, neoplasms, coagulopathy, history of gastric surgery, taking antibiotics,proton pump inhibior and /or histamin2 receptor antagonist during the previous2 weeks,concomitant use ofanticoagulant and/or corticosteroid, and previous
history of allergic reaction to any medications used in
this study.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Helicobacter pylori eradication rate. Timepoint: Ten weeks after starting treatment. Method of measurement: urea breath test(UBT).
- Secondary Outcome Measures
Name Time Method Drug adverse effect rate. Timepoint: Two weeks after starting treatment. Method of measurement: Data gathering sheet.;Patient compliance rate. Timepoint: Two weeks after starting treatment. Method of measurement: Remained pill count.