Prevalence of Hypovolemia and Heart Failure in Non-cardiac Surgery

Completed

• Conditions: Hypovolemia; Diastolic Dysfunction; Heart Failure; Systolic Dysfunction; Venous; Return (Anomaly)

• Registration Number: NCT03349593
• Lead Sponsor: Umeå University

Brief Summary

Prevalence of biventricular function of the heart and preoperative level of venous return is not known in non-cardiac non-morbid obese population.

The aim of the study is to assess the preoperative function of the heart and status of hypovolemia on the day of surgery.

Detailed Description

Preoperative transthoracic echocardiography (TTE) is conducted in 100 individuals. Biventricular function (i.e. systolic and diastolic properties), left ventricular filling pressures and level of venous return are assessed by TTE.

Moreover high-sensitive troponine I and Nt-proBNP, ECG are collected. Multiple echocardiographic parameters will be studied for feasibility in terms of preoperative assessment of the heart.

Study Timeline

• Study First Submitted: 2017-11-17
• Study First Submitted QC: 2017-11-17
• Study First Posted: 2017-11-21
• Study Start: 2017-12-01
• Primary Completion: 2018-11-30
• Study Completion: 2019-12-30
• Status Verified: 2021-12
• Last Update Submitted: 2021-12-15
• Last Update Posted: 2022-01-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• body mass index ≤ 35 kg/m2, electively scheduled for breast cancer surgery, endocrinologic surgery (thyroid, parathyroid) and general abdominal surgery.

Exclusion Criteria

• Not signed consent.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Hypovolemia	One hour before surgery	Screening of preoperative level of venous return
Heart failure	One hour before surgery	Screening of incidence of preoperative systolic and diastolic function

Trial Locations

Locations (1)

Sunderby hospital; 🇸🇪 Luleå, Sweden