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An Observational Study of Hemoglobin Stability in Chronic Kidney Disease Patients on Dialysis Treated With Mircera (Methoxy Polyethylene Glycol-epoetin Beta)

Completed
Conditions
Anemia
Registration Number
NCT01974271
Lead Sponsor
Hoffmann-La Roche
Brief Summary

This prospective, multicenter, observational study will evaluate the impact of comorbidities on hemoglobin stability in chronic kidney disease patients on dialysis treated with Mircera (methoxy polyethylene glycol-epoetin beta). Eligible patients will be followed for 6 months of treatment.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
661
Inclusion Criteria
  • Adult patients, >/= 18 years of age
  • Chronic kidney disease patients on hemodialysis or hemodiafiltration for at least 3 months
  • Previously treated with an erythropoietin stimulating agent (ESA)
  • Patient for whom the investigator decided to initiate treatment with Mircera for medical reasons
  • Last hemoglobin level before initiation of Mircera within the range of 10-12 g/dL
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Exclusion Criteria
  • Current participation in a clinical trial on renal anemia
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Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Percentage of patients with a variation of Hb level of +/- 1 g/dL between the first Mircera injection and Month 66 months
Secondary Outcome Measures
NameTimeMethod
Monthly dose of Mircera6 months
Percentage of patients with Hb value within the range of 10 - 12 g/dL6 months
Change in Hb levelfrom baseline to Month 6
Safety: Incidence of adverse events6 months
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