Multi-center randomized controlled study of Chuanhuang prescription combined with reduced glutathione regimen in 2-4 CKD with 1-2 grade AKI

Phase 1

Recruiting

• Conditions: A on C

• Registration Number: ITMCTR2100004427
• Lead Sponsor: Shanghai Municipal Hospital of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. Subjects meeting the diagnostic criteria of ckd 2-4 and acute kidney injury grade 1-2;
2. Subjects who meet the diagnostic criteria of TCM syndrome of spleen kidney deficiency and toxin stasis combination;
3. 24hu Pro =2.5g;
4. Subjects aged 18-75 years old;
5. Volunteers to participate in this clinical trial and sign the informed consent.

Exclusion Criteria

1. Women who are pregnant or preparing for pregnancy and lactation;
2. Patients with serious primary diseases of other organs in urgent need of immediate treatment, or patients with consumption system diseases such as malignant tumor and active tuberculosis;
3. Patients with anorectal diseases not suitable for enema
4. Patients after renal transplantation;
5. Psychotic patients, unable to cooperate;
6. Subjects allergic to therapeutic drugs;
7. Subjects who are participating in other drug clinical trials or who have participated in other clinical trials within 3 months.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
IL-18;Scr;eGFR;Neutrophil gelatinase-associated lipoprotein, NGAL;BUN;Y-GT;TNFa;IL-16;24hU-pro;