NL-OMON37315已完成不适用
Reflux symptoms in patients with achalasia. - Reflux symptoms in achalasia
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Treated achalasia patients WITH gastroesophageal reflux symptoms
- •1) Diagnosis of idiopathic achalasia confirmed by esophageal manometry that shows the following criteria:
- •- Aperistalsis or simultaneous contractions in the esophageal body.
- •- LES dysrelaxation.
- •2) Treatment of achalasia with one of the following procedures:
- •- Endoscopic balloon dilatation
- •- Surgical Heller myotomy
- •- Per-oral endoscopic myotomy (POEM)
- •3) Minimum total score on the GastroEsophageal Reflux Disease Questionnaire (GERDQ) of * 8.
- •4) Gastroesophageal symptoms after treatment lasting more than 3 months.
- •5) Age 18-80 years.
- •6) Written informed consent.;Treated achalasia patients WITHOUT gastroesophageal reflux symptoms
- •1) Diagnosis of idiopathic achalasia confirmed by esophageal manometry that shows the following criteria:
- •- Aperistalsis or simultaneous contractions in the esophageal body.
- •- LES dysrelaxation.
- •2) Treatment of achalasia with one of the following procedures:
- •- Endoscopic balloon dilatation
- •- Surgical Heller myotomy
- •- Per-oral endoscopic myotomy (POEM)
- •3) Maximum total score on the GastroEsophageal Reflux Disease Questionnaire (GERDQ) of < 8.
- •4) No gastroesophageal symptoms after treatment.
- •5) Age 18-80 years.
- •6) Written informed consent.
排除标准
- •Treated achalasia patients WITH gastroesophageal reflux symptoms
- •- Pseudoachalasia.
- •- Upper gastrointestinal malignancy.
- •- Chagas disease.
- •- Peptic ulcer disease.
- •- Inability to stop PPI, H2-receptor antagonist or prokinetic drug for two weeks.
- •- Presence of an extremely dilated oesophagus body >5 cm.;Treated achalasia patients WITHOUT gastroesophageal reflux symptoms
- •- Pseudoachalasia.
- •- Upper gastrointestinal malignancy.
- •- Chagas disease.
- •- Peptic ulcer disease.
- •- Inability to stop PPI, H2-receptor antagonist or prokinetic drug for two weeks.
- •- Presence of an extremely dilated oesophagus body >5 cm.
研究者
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