Catch the cancer; towards a cfDNA-based test for colorectal cancer screening - CATCA-study

Erasmus MC, Universitair Medisch Centrum Rotterdam0 个研究点目标入组 150 人开始时间: 待定最近更新: 2024年6月24日

适应症

试验速览

暂无简介。

•Individuals participating in the Dutch national colorectal cancer screening program who:
•- Have a positive FIT (fecal immunohistochemical test), prior to sequential colonoscopy (performed in the Erasmus MC);
•- Grant informed consent to participate in this study;;Lynch Syndrome carriers under surveillance of gastroenterologists in the Erasmus MC, who:
•- Have proven Lynch syndrome (DNA mismatch repair mutation);
•- Are >=18 years;
•- Grant informed consent to participate in this study.

•Individuals participating in the Dutch national colorectal cancer screening program who:
•- Are known to be carrier of a genetic predisposition for colorectal cancer (for example Familial Adenomatous Polyposis or MUTYH Associated Polyposis);
•- Have a negative FIT;
•- Have a positive FIT with sequential colonoscopy already performed;
•- Are unwilling to undergo colonoscopy or receive unexpected, but relevant and actionable findings;
•- Underwent a failed colonoscopy;;Lynch Syndrome carriers who:
•- Are unwilling to undergo colonoscopy or receive unexpected, but relevant and actionable findings;
•- are <18 years;
•- underwent a failed colonoscopy.

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