NL-OMON48193
Completed
Not Applicable
Catch the cancer; towards a cfDNA-based test for colorectal cancer screening - CATCA-study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- colorectal cancer
- Sponsor
- Erasmus MC, Universitair Medisch Centrum Rotterdam
- Enrollment
- 150
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Individuals participating in the Dutch national colorectal cancer screening program who:
- •\- Have a positive FIT (fecal immunohistochemical test), prior to sequential colonoscopy (performed in the Erasmus MC);
- •\- Grant informed consent to participate in this study;;Lynch Syndrome carriers under surveillance of gastroenterologists in the Erasmus MC, who:
- •\- Have proven Lynch syndrome (DNA mismatch repair mutation);
- •\- Are \>\=18 years;
- •\- Grant informed consent to participate in this study.
Exclusion Criteria
- •Individuals participating in the Dutch national colorectal cancer screening program who:
- •\- Are known to be carrier of a genetic predisposition for colorectal cancer (for example Familial Adenomatous Polyposis or MUTYH Associated Polyposis);
- •\- Have a negative FIT;
- •\- Have a positive FIT with sequential colonoscopy already performed;
- •\- Are unwilling to undergo colonoscopy or receive unexpected, but relevant and actionable findings;
- •\- Underwent a failed colonoscopy;;Lynch Syndrome carriers who:
- •\- Are unwilling to undergo colonoscopy or receive unexpected, but relevant and actionable findings;
- •\- are \<18 years;
- •\- underwent a failed colonoscopy.
Outcomes
Primary Outcomes
Not specified
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