Effect of Oxytocin Infusion on Blood Loss During Abdominal Myomectomy
- Registration Number
- NCT03308643
- Brief Summary
To evaluate the effects of oxytocin infusion during abdominal myomectomy.
- Detailed Description
Myomectomy is indicated for symptomatic uterine fibroids. Fibroids have blood supply and 20% of the abdominal myomectomy cases might require blood transfusion because of the nature of the surgery. Oxytocin infusion is one of the intervention to decrease blood loss during myomectomy. To evaluate the effects and benefits of oxytocin infusion during abdominal myomectomy we decide to conduct this randomized study.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 100
Inclusion Criteria
- Age 18-50
- Patients who are candidate for abdominal myomectomy
Exclusion Criteria
- History of previous myomectomy.
- Suspected malignancy
- Patients with preoperative anemia
- Patients using hormonal treatments before the surgery.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Placebo saline Patients will receive pure normal saline infusion at the same rate and volume just before the surgery after the induction of general anesthesia. Oxytocin infusion Oxytocin Patients will receive intravenous oxytocin infusion just before the surgery after the induction of general anesthesia.
- Primary Outcome Measures
Name Time Method Blood loss during surgery 2 hours estimated blood loss during the surgery measured by aspiration fluid.
- Secondary Outcome Measures
Name Time Method Blood loss after abdominal myomectomy 1 hour postoperatively change in Hematocrit Percentage (before and after the surgery)
Trial Locations
- Locations (1)
Kanuni Sultan Suleyman Egitim ve Arastırma Hastanesi
🇹🇷İstanbul, Turkey