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The Effect Of Antihypertensive Treatment With Lisinopril and Labetalol on Baroreflex Sensitivity in Stroke - Effect Of Lisinopril and Labetalol On BRS In Stroke

Conditions
Stroke
Registration Number
EUCTR2004-004231-53-GB
Lead Sponsor
Royal Devon and Exeter NHS Foundation Trust
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
All
Target Recruitment
23
Inclusion Criteria

Age >18 years
Clinical diagnosis of stroke
Clinical indication for antihypertensive treatment
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

Contraindication to trial medication (beta blockers and ace inhibitors)
Clinical indication for beta blockers and ace inhibitors other than hypertension

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Main Objective: To assess the effect of Lisinopril and Labetalol on baroreflex sensitivity in patients with cerebrovascular disease.;Secondary Objective: To assess whether any changes in baroreflex sensitivity observed are associated with changes in arterial compliance.;Primary end point(s): Change in baroreflex sensitivity
Secondary Outcome Measures
NameTimeMethod
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