A clinical study on the effects of beverage containing probiotics on glucose metabolism in healthy adults.

Not Applicable

• Conditions: Healthy adults

• Registration Number: JPRN-UMIN000023480
• Lead Sponsor: KSO Co., Ltd

Brief Summary

1.Intake of beverage containing probiotics reduced 2 hour plasma glucose level during OGTT at 8 weeks. 2.Intake of beverage containing probiotics improved insulin resistance. 3.Intake of beverage containing probiotics increased fecal bifidobacteria.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2016-12-04
• Study Start: 2017-10-07
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

Not provided

Exclusion Criteria

1. Subjects routinely taking medicine as well as administration of medication which may influence blood glucose level. 2. Subjects routinely taking health food or supplement which may influence glucose metabolism. 3. Subjects with diabetes. 4. Subjects who are under medication or have serious diseases. 5. Subjects who have surgical history such as gastrointestinal disease. 6. Subject who regularly undertakes medication or treatment that affects bowel motion (such as: antibiotics, antiflatulents, laxatives, antidiarrheal drug). 7. Subjects who regularly consume functional food/nutraceuticals, health supplements (such as: lactic acid bacteria, bifidobacteria, oligosaccharides, dietary fiber) antiflatulents and/or laxatives in common use. 8. Subjects who habitually consume fermented foods during the study period. 9. Subjects who are under treatment or have a history of drug/alcohol dependence. 10. Subjects who are planned to become pregnant after informed consent for the current study or are pregnant or lactating. 11. Subjects with allergic to test products used in the study. 12. Subjects who participate in other clinical or plan to other clinical trials during this study period. 13. Subjects who are judged as unsuitable for the study by the investigator for other reason.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Plasma glucose level and area under the curve of plasma glucose during 75 g oral glucose tolerance test.

Secondary Outcome Measures

Name	Time	Method
Insulin resistance, fasting blood glucose level, Hemoglobin A1c (HbA1c), blood short chain fatty acid, fecal bifidobacteria.