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Analgesia Comparison of Nalbuphine and Morphine for Laparoscopic Myomectomy

Phase 4
Conditions
Postoperative Pain
Interventions
Registration Number
NCT03288428
Lead Sponsor
Peking University First Hospital
Brief Summary

to compare the analgesia and side effect of nalbuphine and morphine for elective Laparoscopic myomectomy.

Detailed Description

To compare the analgesia and side effect of nalbuphine and morphine for elective Laparoscopic myomectomy, by using patient controlled analgesia postoperatively, a randomized, double blind clinical trial. Patients undergoing elective Laparoscopic myomectomy are randomly divided into two groups: nalbuphine and morphine groups. All patients are under general anesthesia with routine methods. The nalbuphine group receive postoperative patient controlled analgesia using nalbuphine 30mg/120ml, while the morphine group receive postoperative patient controlled analgesia using morphine 60mg/120ml. Perioperative parameters are to be collected to compare the two groups.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
80
Inclusion Criteria
  • elective Laparoscopic myomectomy patients 24hr post-operative patient controlled analgesia analgesia no mild or severe liver or renal disfunction
Exclusion Criteria
  • can't understand patient controlled analgesia device refuse trial

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
nalbuphineNalbuphineusing nalbuphine for patient controlled analgesia
morphineMorphineusing morphine for patient controlled analgesia
Primary Outcome Measures
NameTimeMethod
numerical rating scale24 hr post-operatively

1-10

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

First hospital Peking University

🇨🇳

Beijing, Beijing, China

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