Evaluation of pain in severe head injury patients admitted to Neurointensive Care
Not Applicable
- Conditions
- Health Condition 1: S06- Intracranial injury
- Registration Number
- CTRI/2022/02/040072
- Lead Sponsor
- ational Institute of Mental Health and Neurosciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Age >18 and < 65 years
2. Severe TBI patients requiring MV > 24 h
Exclusion Criteria
1. Patients with cardiac arrhythmias/ severe cardiac disease
2. Patients with neuromuscular disorders
3. Patients with spinal shock
4. Patients on beta-blockers / antiarrhythmic drugs / anticholinergic drugs
5. Patients with major cognitive impairment (malignant stroke, post-cardiac arrest)
6. Patients with GCS 3
7. Pregnancy
8. Refusal to consent
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Assessment of pain by ANI and its comparison with the Critical Pain Observation Tool-Neuro in severe TBI patientsTimepoint: Pain assessment will be done once a day, pre and post stimulus, on day 2 and day 4 of ICU admission
- Secondary Outcome Measures
Name Time Method 1. Correlate nociceptive levels (ANI) with the level of consciousness (using Patient State Index/BIS/Entropy). <br/ ><br>2. Correlate nociceptive levels (ANI) with the level of autonomic dysfunction (using Heart Rate variability). <br/ ><br>Timepoint: Correlation will be done using data collected on day 2 and day 4 of ICU admission