Meniscus Repair With Simultaneous ACL Reconstruction: Clinical Outcomes，Failure Rates And Subsequent Processing

Completed

• Conditions: Meniscus Injury; The ACL Rupture
• Interventions: Procedure: Meniscus repair; partial meniscectomy

• Registration Number: NCT04455516
• Lead Sponsor: Peking University Third Hospital

Brief Summary

Our study has explored the causes of failure of meniscus repair and investigated the clinical effects of partial meniscectomy when meniscus repair failed.

Detailed Description

Background: Meniscus repair performed during ACL reconstruction may fail and the subsequent treatment includes revision meniscal repair or partial meniscectomy.

Purpose: To retrospectively analyze the clinical outcomes of meniscus repair with simultaneous anterior cruciate ligament (ACL) reconstruction and explore the causes of failure of meniscus repair.

Methods: From May 2013 to July 2018, the clinical data of 165 patients who were treated with meniscus surgery and simultaneous ACL reconstruction by the same doctor, including 69 cases of meniscus repair (repair group) and 96 cases of partial meniscectomy (partial meniscectomy group), were retrospectively analyzed. The 69 patients of the repair group were divided into the nonfailure group (62 cases) and the failure group (7 cases) depending on the repair effect. The average follow-up period was 38 (±10.5) months. Postoperative outcomes of the repair group and the partial meniscectomy group were compared. General conditions and postoperative outcomes of the failure group and the nonfailure group were compared. Seven patients in the failure group who underwent second arthroscopy were followed up for 30 (±17.4) months, and their postoperative outcomes were summarized.

Study Timeline

• Study Start: 2020-03-16
• Primary Completion: 2020-04-16
• Study Completion: 2020-05-16
• Study First Submitted: 2020-06-25
• Status Verified: 2020-07
• Study First Submitted QC: 2020-07-01
• Last Update Submitted: 2020-07-01
• Study First Posted: 2020-07-02
• Last Update Posted: 2020-07-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 165

Inclusion Criteria

1. patients with intraoperatively confirmed ACL rupture combined with medial, lateral, or medial and lateral meniscal injury;
2. age <60 years
3. no history of previous ipsilateral knee meniscal injury.

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Exclusion Criteria

1. ACL rupture associated with fracture, collateral ligament injury, or complex ligament injury;
2. a history of knee surgery;
3. a significant degree of osteoarthritis.

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
nonfailure group	Meniscus repair; partial meniscectomy	These patients had a successful first operation
repair group	Meniscus repair; partial meniscectomy	The first operation in these patients was meniscus repair
failure group	Meniscus repair; partial meniscectomy	In these patients, the first meniscus repair operation failed

Primary Outcome Measures

Name	Time	Method
The result of partial meniscus resection	Two years after the surgery	Clinical signs were assessed after the surgery, including swelling of the joint, tenderness at the joint line, locked-in syndrome, and positive McMurray's sign.
Lysholm scores	Two years after the surgery	The minimum is 0, the maximum is 100, and the higher the score, the better the result
International Knee Documentation Committee（IKDC）scores	Two years after the surgery	The minimum is 0, the maximum is 100, and the higher the score, the better the result
Visual analog scale (VAS) scores	Two years after the surgery	The minimum is 0, the maximum is 10, and the higher the score, the worse the result

Trial Locations

Locations (1)

Peking University Third Hospital; 🇨🇳 Beijing, Beijing, China