Genetics of Cardiovascular and Neuromuscular Disease

Recruiting

• Conditions: Cardiomyopathy; Muscular Dystrophy; Arrhythmia

• Registration Number: NCT00138931
• Lead Sponsor: University of Chicago

Brief Summary

We are studying the genetics of human cardiovascular and neuromuscular disease. There are many different genetic regions that have been associated with the development of cardiomyopathy. An equal number of genetic regions have been associated with muscular dystrophy and there is overlap because some of the identical genes, when mutated, produce both cardiomyopathy and muscular dystrophy. We are working to identify genes and gene mutations associated with cardiomyopathy, arrhythmias and muscular dystrophy. We propose to screen these samples for mutations in genes known to be involved in these disorders.

Detailed Description

Not available

Study Timeline

• Study Start: 1996-09
• Study First Submitted: 2005-08-29
• Study First Submitted QC: 2005-08-29
• Study First Posted: 2005-08-30
• Status Verified: 2024-07
• Last Update Submitted: 2024-07-25
• Last Update Posted: 2024-07-26
• Primary Completion: 2026-01
• Study Completion: 2026-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 2000

Inclusion Criteria

• Patients of all ages will be considered for the study. In particular, families with more than one affected relative will be sought.

Exclusion Criteria

• Subjects without a suspected inherited cardiovascular or neuromuscular disorder will be excluded from this study.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Identification of genetic causes of cardiomyopathy	unlimited

Trial Locations

Locations (1)

University of Chicago; 🇺🇸 Chicago, Illinois, United States