The effect of intravenous lidocaine to prevent intracranial pressure increase in endotracheal intubation assessed by optic nerve sheath diameter<br>

Not yet recruiting

• Conditions: brain pressure; Intracranial pressure; 10022114; 10021666

• Registration Number: NL-OMON47899
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

Patients aged >18 year old, scheduled for elective surgery under general anesthesia with a planned duration of the procedure > 30 min that can be routinely performed with a ETI.

Exclusion Criteria

- Surgery of the eye an eye region
- Neurosurgical procedure and neurosurgical procedure in the past
- Neurological disorders
- Bilateral eye trauma
- Glaucoma
- Mentally retarded patients
- Contraindications for the use of lidocaine e.g.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Difference in optic nerve sheet diameter in millimetre before, during and after<br /><br>intubation between both groups.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Time taken for the ONSD to return back to its initial value once the patients<br /><br>is intubated. </p><br>