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临床试验/NCT01082458
NCT01082458已完成不适用

Comparison of Lidocaine and Remifentanil for the Effect on Responses to the Endotracheal Tube During Emergence From General Anesthesia

Yonsei University2 个研究点 分布在 2 个国家目标入组 67 人开始时间: 2010年2月最近更新:
适应症
相关药物

试验速览

阶段
不适用
状态
已完成
入组人数
67
试验地点
2
主要终点
Comparison of lidocaine and remifentanil for the effect on responses to the endotracheal tube during emergence from general anesthesia

研究概览

简要总结

Target concentration infusion(TCI) of remifentanil (2.0ng/ml) suppresses the cough induced by endotracheal tube more effectively than intravenous administration of lidocaine (1.5mg/kg).

研究设计

研究类型
Interventional
主要目的
Prevention

入排标准

年龄范围
20 Years 至 —(Adult, Older Adult)
性别
Female
接受健康志愿者

入选标准

  • Females older than 20 years old

排除标准

  • Patients with acute or chronic respiratory disease, hypertension, gastro-esophageal reflux disease, having preoperative sedatives or mucolytics, and current smoker.

结局指标

主要结局

Comparison of lidocaine and remifentanil for the effect on responses to the endotracheal tube during emergence from general anesthesia

The incidence and the grade of cough during emergence from general anensthesia between remifentanil TCI group and lidocaine IV administration group.

次要结局

未报告次要终点

研究者

申办方类型
Other

研究点 (2)

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