Once weekly folic acid supplementation in Malaysian wome

Not Applicable

Completed

• Conditions: Red blood cell folate; Diet and Nutrition - Other diet and nutrition disorders; Public Health - Other public health

• Registration Number: ACTRN12619000818134
• Lead Sponsor: South Australian Health and Medical Research Institute (SAHMRI)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-06-06
• Study Completion: 2020-02-13
• Last Update Posted: 7 December 2020

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 331

Inclusion Criteria

Non-pregnant (self-reported), not planning on becoming pregnant, not currently taking micronutrient supplements containing folic acid or participating in another nutritional intervention, not taking any medication known to inhibit folate status (methotrexate, anti-convulsants, or sulphasalazine), and not planning to leave the community for the timeline of the study.

Exclusion Criteria

Pregnant, planning on becoming pregnant, currently taking micronutrient supplements containing folic acid or participating in another nutritional intervention, taking any medication known to inhibit folate status (methotrexate, anti-convulsants, or sulphasalazine), or planning to leave the community in durations that would interfere with the study timeline.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Red blood cell folate (nmol/L)<br>Measurement: Microtiter technique with chloramphenicol-resistant Lactobacillus casei as the test microorganism. This will be calculated from whole blood folate by subtracting plasma folate and correcting for haematocrit. [16 weeks (post-treatment)]