TDCS in Acute Stroke

Not Applicable

• Conditions: Stroke

• Registration Number: NCT01701713
• Lead Sponsor: Charite University, Berlin, Germany

Brief Summary

The purpose of this study is to determine the safety of transcranial direct current stimulation in aphasia therapy in acute and post-acute stroke.

Detailed Description

TDCS has been shown to have a positive effect on clinical outcome in both motor rehabilitation and aphasia treatment in chronic aphasic patients. In healthy subjects the method sped up reaction times in naming and language learning tasks. In TDCS a weak current is applied to the subjects head increasing excitatory activity which might lead to improved brain function.

Study Timeline

• Study Start: 2009-06
• Study First Submitted: 2012-09-26
• Status Verified: 2012-10
• Study First Submitted QC: 2012-10-04
• Study First Posted: 2012-10-05
• Last Update Submitted: 2012-10-05
• Last Update Posted: 2012-10-08
• Primary Completion: 2013-06
• Study Completion: 2013-06

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• first media stroke
• language impairment
• informed consent
• right handedness
• NIHSS < 20

Exclusion Criteria

• previous Epilepsy oder epileptogenic events
• epilepsy typical elements in EEG
• hypersensitive skin (head)
• metal implants (head)
• pace maker or other electronic implants
• previous head/brain surgery
• medication reducing seizure threshold
• previous psychiatric events

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
skin irritation	2 months

Secondary Outcome Measures

Name	Time	Method
Improved language	2 months	improved picture naming

Trial Locations

Locations (2)

Brandenburg Klinik Bernau; 🇩🇪 Bernau, Brandenburg, Germany

Charité, Campus Benjamin Franklin, Dep. of Neurology; 🇩🇪 Berlin, Germany