TDCS in Acute Stroke
Not Applicable
- Conditions
- Stroke
- Interventions
- Device: DKI ED2011Device: Sham-TDCS
- Registration Number
- NCT01701713
- Lead Sponsor
- Charite University, Berlin, Germany
- Brief Summary
The purpose of this study is to determine the safety of transcranial direct current stimulation in aphasia therapy in acute and post-acute stroke.
- Detailed Description
TDCS has been shown to have a positive effect on clinical outcome in both motor rehabilitation and aphasia treatment in chronic aphasic patients. In healthy subjects the method sped up reaction times in naming and language learning tasks. In TDCS a weak current is applied to the subjects head increasing excitatory activity which might lead to improved brain function.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
- first media stroke
- language impairment
- informed consent
- right handedness
- NIHSS < 20
Exclusion Criteria
- previous Epilepsy oder epileptogenic events
- epilepsy typical elements in EEG
- hypersensitive skin (head)
- metal implants (head)
- pace maker or other electronic implants
- previous head/brain surgery
- medication reducing seizure threshold
- previous psychiatric events
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description TDCS - DKI ED2011 DKI ED2011 TDCS with DKI ED2011 session is followed by a behavioral naming therapy with different cues Sham-TDCS Sham-TDCS Sham-TDCS session is followed by a behavioral naming therapy with different cues
- Primary Outcome Measures
Name Time Method skin irritation 2 months
- Secondary Outcome Measures
Name Time Method Improved language 2 months improved picture naming
Trial Locations
- Locations (2)
Charité, Campus Benjamin Franklin, Dep. of Neurology
🇩🇪Berlin, Germany
Brandenburg Klinik Bernau
🇩🇪Bernau, Brandenburg, Germany