The effect of vinegar co-ingestion on postprandial glucose control in type 2 diabetes patients.

Completed

• Conditions: adult-onset diabetes; type 2 diabetes; 10018424

• Registration Number: NL-OMON34405
• Lead Sponsor: Maastricht University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

Male type 2 diabetes patients:
-40-70 yrs.
-BMI 25-35 kg/m2
-oral blood glucose lowering medication;Male control subjects:
-40-70 jr.
-BMI 25-35 kg/m2

Exclusion Criteria

Exogenous insulin therapy; HbA1c <6.5% or >10.0%; diagnosed impaired renal or liver function; morbid obesity (BMI>35 kg/m2); incident cardiovascular events in the last year (heart attack, stroke, aneurysms). Furthermore, subjects with an ulcus pepticum, ulcus duodeni, ulcus ventriculi and/or oesophagal reflux will be excluded. In addition, subjects using antacids, H-2-receptor blockers, proton pump inhibitors, NSAID*s, and/or prokinetic agents will be excluded.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Main study parameter/endpoint<br /><br>• Postprandial plasma glucose concentration<br /><br>• Postprandial plasma insulin concentration<br /><br>• Hyperglycemia (glucose concentration >10mmol/L)</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary study parameters/endpoints<br /><br>• Energy expenditure (derived from physical activity record)<br /><br>• Dietary intake (derived from dietary record) </p><br>