Chronic effects of pungent ingredients of ginger on energy expenditure by brown adipose tissue in humans

Not Applicable

• Conditions: Healthy male volunteers

• Registration Number: JPRN-UMIN000012974
• Lead Sponsor: Tenshi College, School of Nursing and Nutrition, Department of Nutrition

Brief Summary

ine healthy male volunteers participated in the present study. Before and after daily ingestion of either Grains of Paradise extract (GP, 40 mg/day) or placebo (GP 0 mg/d) for 5 wk, whole-body energy expenditure (EE) was measured at thermoneutral condition (27˚C) and after 2-h cold exposure at 19˚C. Body fat content was also monitored. Resting EE at thermoneutral condition did not change after either the GP and placebo treatments. Response of EE to acute cold exposure (CIT) increased and body fat content decreased significantly after the 5-wk GP treatment. The placebo treatment did not change CIT and body fatness. As CIT is predicted index of BAT activity, our results suggest that repeated ingestion of GP recruits BAT and thereby increases EE and decreases body fatness.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2013-03-30
• Study Start: 2014-01-30
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: Male
• Target Recruitment: 15

Inclusion Criteria

Not provided

Exclusion Criteria

Body mass index >=30

Study & Design

• Study Type: Interventional
• Study Design: Not specified