The Effect of Probiotic Mouthrinse in Fixed Orthodontics Patients
Phase 3
- Conditions
- The amount of Streptococcus mutans in the dental plaque around the orthodontic brackets of the 6 maxillary anterior teeth.Dental caries, unspecified
- Registration Number
- IRCT20180901040922N1
- Lead Sponsor
- Sari University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 48
Inclusion Criteria
Systemic Health
The Habit of Brushing Twice a Day
Permanent Dentition
The Presence of Orthodontic Fixed Appliances on At least Eight Maxillary Anterior Teeth
Pass At least Three Months From the Onset of Orthodontic Treatment
Exclusion Criteria
Use of Systemic and Topical Antibiotics as well as any Anti-inflammatory Drug Within Four Weeks Before the Start of the Study
The History of Fluoride Therapy Four Weeks Before the Start of the Study
Consumption of any Probiotic Product and Xylitol Gum From Four Weeks Before the Start of the Study and During the Study
The Presence of Active Lesion of Decay and Periodental disease
Smoking
Sensitivity to Probiotic, Sodium Fluoride and Placebo Mouthrinses
Infectious Diseases
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The amount of Streptococcus mutans in dental plaque. Timepoint: Plaque Sampling Before Intervention and Two Weeks After Using Mouthrinse. Method of measurement: The Number of Colonies grown on selective Culture Media.
- Secondary Outcome Measures
Name Time Method