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Clinical Trials/IRCT20211026052875N1
IRCT20211026052875N1
Recruiting
未知

The effect of mechanical ventilation during cardiopulmonary bypass surgery in adult cardiac valve surgery on inflammatory responses and pulmonary function

Rajaie Cardiovascular, Medical and Research Center0 sites60 target enrollmentTBD

Overview

Phase
未知
Intervention
Not specified
Conditions
Not specified
Sponsor
Rajaie Cardiovascular, Medical and Research Center
Enrollment
60
Status
Recruiting
Last Updated
4 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
4 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
Rajaie Cardiovascular, Medical and Research Center

Eligibility Criteria

Inclusion Criteria

  • ?All adult patients with age \>35y undergoing elective cardiac valve surgery

Exclusion Criteria

  • patients undergoing emergency surgery
  • Patients undergoing congenital heart surgery
  • Patients undergoing third and more valve resections
  • Patients with coagulation disease
  • Patients undergoing dialysis
  • Patients with pulmonary problems such as COPD who are in stage one and four due to FEV1 ( stage1:mild FEV1\=80%? stage2:moderate FEV1 50\-79%? stage3:severe FEV130\-49% ? stage 4: very severe FEV1 \=30% )
  • Patients with fractional ejection less than 35%,
  • Patients who transfer to the ICU with open sternum
  • In this study, if the surgeon's vision decreases during cardiac surgery due to continued mechanical ventilation, the ventilation will stop and the patient will be excluded from the study
  • Patients who remain intubated for more than 12 hours after transfer to the ICU due to hemodynamic instability

Outcomes

Primary Outcomes

Not specified

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