Preventive Cognitive Therapy with Neurocognitive Remediation Therapy for partially remitted depressed patients: a pragmatic randomized controlled multicentre trial.
- Conditions
- Major Depressive Disorder
- Registration Number
- NL-OMON22498
- Lead Sponsor
- Amsterdam UMC, location AMC
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 115
Inclusion Criteria
Does not meet the criteria of a current MDD episode according to the DSM-5, as assessed with the Structured Clinical Interview for DSM-5 disorders (SCID-5-S; First et al., 2016);
- Is more than 8 weeks MDD diagnosis-free (with a maximum of 2 years);
- Has a Hamilton Depression Interview (HAM-D) score of =8 and =15 (Hamilton, 1980);
- Is aged 18 or older;
- Speaks Dutch or English.
Exclusion Criteria
- Current (hypo)mania or a history of bipolar illness;
- Any psychotic disorder;
- Alcohol or drug misuse;
- Primary Anxiety disorder diagnosis;
- Electroconvulsive therapy in the previous 12 months;
- Neurological disorder;
- Disabling sensory and/or motor deficit.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Depressive symptoms over a one-year period: this main study parameter will be assessed monthly during a one-year period after baseline assessment using the Inventory of Depressive Symptomatology (IDS-SR).
- Secondary Outcome Measures
Name Time Method