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临床试验/ITMCTR2000003058
ITMCTR2000003058招募中1 期

Study on the brain effect of scalp acupuncture treatment of vascular dementia based on DTI

Shuguang Hospital Affiliated to Shanghai University of TCM0 个研究点开始时间: 待定最近更新:
适应症

试验速览

阶段
1 期
状态
招募中
发起方

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional study

入排标准

年龄范围
40 至 80(—)
性别
All

入选标准

  • 1. Right-handed, aged40-80 years, regardless of gender;
  • 2. MRI and / or CT support the existence of ischemic cerebrovascular disease, which accords with the diagnostic criteria of NINDS-AIREN;
  • 3. The education level above primary school (including primary school);
  • 4. Meets the diagnostic criteria of dementia (DSM-IV);
  • 5. Meeting the probable VaD diagnostic criteria of NINDS-AIREN;
  • 6. Modified Hachinski Ischemia scale (MHIS), total score >= 4;
  • 7. Patients with mild or moderate severity: 10 <= MMSE <= 26 and 1 <= CDR <= 2;
  • 8. Hamilton depression scale, HAMD total score of Hamilton Depression scale <= 17;
  • 9. There is no taboo on MRI scanning.

排除标准

  • 1. There was memory or other cognitive dysfunction in the past, but no obvious ischemic focus on the image;
  • 2. With cognitive impairment caused by trauma, tumor, infection, thyroid dysfunction, alcoholism, etc;
  • 3. With severe vision, hearing impairment and aphasia, affect the examination or can not cooperate with the dementia scale evaluation or can not cooperate with the head immobilization; 4. With anxiety, depression, mental disorder and disturbance of consciousness;
  • 5. With abnormal laboratory indexes;
  • 6. With severe circulatory, respiratory, urinary, digestive, hematopoietic diseases (such as unstable angina pectoris, uncontrollable asthma, active gastric hemorrhage, etc.) and cancer;
  • 7. Pregnant or lactating women;
  • 8. With history of brain trauma or cerebral hemorrhage within 1 month;
  • 9 With contraindications for MR examination;
  • 10. Taken a acupuncture treatment in the past 4 weeks;
  • 11. Unable to complete the basic course of treatment, poor compliance (that is, unable to adhere to treatment) and difficult to follow up in the future.

研究者

发起方
Shuguang Hospital Affiliated to Shanghai University of TCM

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