Effect of a Structured Academic Yoga Program on telomere length in Healthy Volunteers: A Randomized Controlled Trial
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- High-throughput
研究概览
简要总结
This randomized controlled trial aims to investigate the effect of a structured academic yoga program on telomere length in healthy volunteers. Telomere structures naturally shorten with age, and their accelerated erosion is associated with various age-related diseases and poor health outcomes. Yoga may positively influence telomere length and consequently ,cellular aging .The Study involves 20 participants aged 18 -30 years from the International Institute of Yoga and Naturopathy Medical Sciences (IIYNMS),Chengalpattu. Participants will engage in one hour of regular academic yoga practice, five days a week, for six months. The interventional effectiveness is assessed through measuring the Changes in Telomere length using High-throughput Quantitative Fluorescence In Situ Hybridization (HT-Q-FISH) at baseline and post intervention. By examining the biological and psychological outcomes of yoga practice, this study seeks to provide scientific evidence on its potential as a preventive health strategy for enhancing cellular longevity and overall well-being.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 30.00 Year(s)（—）
- 性别
- All
入选标准
- •Healthy volunteers aged 18–30 years. Individuals scoring within the normal range (score less than or equal to 3) on a validated health screening tool (General Health Questionnaire.
- •GHQ-12). Individuals willing to participate in yoga sessions and provide informed consent. No history of chronic illness or recent major medical interventions.
排除标准
- •Individuals currently practicing yoga or other mind-body interventions regularly.
- •Pregnant or lactating women.
- •Individuals using medications or supplements known to influence oxidative stress, inflammation, or telomere dynamics.
结局指标
主要结局
High-throughput
时间窗: Telomere length changes are assessed before and after the intervention period of 6 months.
Quantitative Fluorescence In Situ Hybridization (HT-Q-FISH): A sensitive and precise method that quantifies Mean telomere length (MTL) in kilobases per cell, Percentage of critically short telomeres,Telomere length distribution across leukocyte subsets.
时间窗: Telomere length changes are assessed before and after the intervention period of 6 months.
次要结局
- Perceived Stress Scale (PSS):Tool to measure perception of stress in daily life.(WHO-5 Well-Being Index:To assess the subjective psychological well being.)
研究者
Dr A Velan
International Institute of Yoga and Naturopathy Medical Sciences