KCT0002264
Recruiting
N/A
Identification of predictive biomarkers for treatment outcome in patients with advanced hepatocellular carcinoma
ConditionsDiseases of the digestive system
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Diseases of the digestive system
- Sponsor
- Yonsei University Health System, Severance Hospital
- Enrollment
- 100
- Status
- Recruiting
- Last Updated
- 7 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •? unresectable primary liver cancer
- •? Age 20 years old or older
- •? Whole body performance (ECOG) 0\-2
- •? Child\-Pugh score is B or more
- •? Minimum volume of normal liver without tumor invasion\> 1000cm3
- •? Minimum distance between target and organ at risk (eg duodenum, stomach) \= 0\.5cm
- •? Adequate \*LFT (\*AST / \*ALT \<5 x upper limit of normal, total bilirubin\> \<3 mg / dl, albumin\> 2\.5 g / dL, normal \*PT / \*PTT)
- •? Adequate renal function (creatinine \<1\.8 mg / dl or \*Ccr\> 50 ml / min)
- •? \*BM reserve (\*ANC \=1500 / mm3, \*PLT \=50000 / mm3, \*Hb\> 9 g / dl)
- •? lesion that can be measured or evaluated on CT
Exclusion Criteria
- •? Those who can not perform respiratory training for treatment design
- •? Patients with a history of previous abdominal radiation therapy
- •? Those who can not receive consent before treatment
- •? Those who do not agree to contraception as a pregnant patient
Outcomes
Primary Outcomes
Not specified
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