Temporal Realistic Assessment of the Fungal Infection Incidence Across Canada for High Risk Subjects With Hematological Disease (TRAFIC)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 130
- 主要终点
- Percentage of Participants With Non-Candida Invasive Fungal Infections at a Single Institution
研究概览
简要总结
This will be a retrospective study that includes retrospective chart reviews at major institutions across Canada. The intent of the study is to generate both regional and national incidence data for non-Candida invasive fungal infections (IFI) in high risk participants. The study will include participants receiving stem cell transplant and high dose chemotherapy treatment for leukemia.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •To be eligible for study inclusion, the participant must have:
- •A hematological malignancy requiring high dose chemotherapy with or without bone marrow transplant
排除标准
- •The participant is not eligible for study inclusion if:
- •Their IFI is not related to hematological malignancies.
结局指标
主要结局
Percentage of Participants With Non-Candida Invasive Fungal Infections at a Single Institution
时间窗: 365 days
Data were extracted from participant hospital records from the time of initiating chemotherapy or conditioning regimen for their stem cell transplant (index date) until one year post-index date, in order to determine the percentage of high risk participants with non-Candida invasive fungal infections.
次要结局
- Percentage of Participants With a Specific Fungal Pathogen at a Single Institution(365 days)
- Percentage of Participants With Invasive Fungal Infections in Canada(365 days)