Disease related to iodine salt lack among people living in Jharkhand

Not Applicable

• Conditions: Health Condition 1: E039- Hypothyroidism, unspecifiedHealth Condition 2: E02- Subclinical iodine-deficiency hypothyroidism

• Registration Number: CTRI/2024/03/063798
• Lead Sponsor: Monit sundriyal

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 1 April 2024

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

i)Age group between (18 - 70 years) will be included in the study.

ii)Patients diagnosed with overt, subclinical hypothyroidism with or without CVD or/CKD metabolic comorbidities.

iii) Controls with euthyroidism without CVD, CKD or autoimmune disorder, inflammatory diseases like (Hashimoto’s thyroiditis, Rheumatoid arthritis and Lupus) immune-compromised will be taken in the study.

Exclusion Criteria

i) Study participants less than 18 years & women with pregnancy will not be included.

ii)The study will not include patients on medication with antithyroid drugs, lipid-lowering drugs, antihypertensives, or any other steroids for inflammatory diseases.

iii) Patients and healthy controls on antioxidant supplementation or other supplements that affect oxidative stress will be excluded from the study.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1)BMI, lipid profile, and inflammatory marker levels may elevate in subclinical hypothyroidism, hypothyroidism, and associated disorders. <br/ ><br>2)Smoking and alcohol may increase the lipid profile & inflammatory marker levels in hypothyroidism patients and associated disorders. <br/ ><br> <br/ ><br>3)Total blood cell counts and iron profile levels may alter in hypothyroidism. <br/ ><br>Timepoint: 1)BMI, lipid profile, and inflammatory marker levels may elevate in subclinical hypothyroidism, hypothyroidism, and associated disorders. (6 months) <br/ ><br>2)Smoking and alcohol may increase the lipid profile & inflammatory marker levels in hypothyroidism patients and associated disorders.(6 months) <br/ ><br> <br/ ><br>3)Total blood cell counts and iron profile levels may alter in hypothyroidism. (6 months) <br/ ><br>

Secondary Outcome Measures

Name	Time	Method
Total blood cell count and iron profile levels may alter in hypothyroidism. <br/ ><br>Timepoint: 6 months