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临床试验/NCT06607354
NCT06607354已完成不适用

The Effect of Consuming Grass Finished Lamb Meat on Omega-3 Blood Response Among Healthy Consumers

Queen's University, Belfast2 个研究点 分布在 1 个国家目标入组 34 人开始时间: 2019年6月20日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
34
试验地点
2
主要终点
Fatty acid (%) change in blood plasma between treatments

研究概览

简要总结

This study will investigate the impact of consuming grass-finished lamb meat on blood omega-3 PUFAs and cardiovascular risk factors compared to concentrate-finished lamb meat. Healthy volunteers will consume three portions of lamb meat/week from a grass-finished meat treatment or a concentrate-finished meat treatment for four weeks. Blood samples will be taken at weeks zero and four. The primary outcome is to assess difference in change in omega-3 PUFA concentration in plasma and platelets between treatment groups. The secondary outcome is to assess between groups differences in change in cardiovascular disease risk factors including blood pressure, BMI and lipids among healthy individuals.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
Single (Participant)

盲法说明

Describe it was the participant

入排标准

年龄范围
18 Years 至 64 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Healthy male and female volunteers aged between 18-64 years old.

排除标准

  • Participants with a BMI of <18.5 km/m² and greater than >35 km/m².
  • Participants who take prescribed medication, including statins to reduce LDL cholesterol, and any form of dietary supplements (excluding vitamin D).
  • People who smoke.
  • Participants who consume more than two portions of fish per month.

结局指标

主要结局

Fatty acid (%) change in blood plasma between treatments

时间窗: Week 0 and week 4

Primary outcome is to assess the impact of consuming grass vs concentrate finished lamb on blood plasma response in healthy volunteers

Fatty acid change (%) in blood plasma phospholipids between treatments

时间窗: Week 0 and week 4

Primary outcome is to assess the impact of consuming grass vs concentrate finished lamb on blood plasma phospholipid response in healthy volunteers

次要结局

  • Change in weight (kg) in participants between treatments(Week 0 and week 4)
  • Change in Body Mass Index (BMI) in participants between treatments - calculated by dividing weight (kg) by height in meters squared(Week 0 and week 4)
  • Cholesterol(Week 0 and week 4)
  • Blood pressure (diastolic and systolic)(Week 0 and week 4)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Lynda Perkins

Postdoctoral Researcher

Queen's University, Belfast

研究点 (2)

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