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Clinical Trials/NCT00082160
NCT00082160CompletedNot Applicable

fMRI Investigation of Meditation

National Center for Complementary and Integrative Health (NCCIH)1 site in 1 country60 target enrollmentStarted: July 2001Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
60
Locations
1

Study Overview

Brief Summary

The purpose of this study is to use brain imaging technology to identify the parts of the brain that are activated during meditation and to compare these parts to those activated during other activities. This study will also determine the effects of meditation on involuntary functions, such as breathing.

Detailed Description

Meditation and relaxation-based interventions are becoming more widely accepted in clinical settings because of their low cost, low risk, and proven effectiveness as a complementary intervention in a wide range of diseases. Despite the success and growing use of relaxation-based treatments, few studies have addressed the basic mechanism by which these treatments work. This study will use functional magnetic resonance imaging (fMRI) to define the brain mechanisms underlying the meditative state, to differentiate this state from other states, and to determine how meditation-induced brain changes affect autonomic function.

Participants in this study will have an fMRI brain scan. Brain activity, breathing rate, and heart rate will be measured while the participant engages in three different activities: lying quietly, meditating, and mentally generating numbers.

Study Design

Study Type
Observational
Observational Model
Defined Population
Time Perspective
Other

Eligibility Criteria

Ages
18 Years to 50 Years (Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Daily practice of Vipassana or Kundalini meditation for at least 1 year and participation in at least one 1-week meditation retreat

Exclusion Criteria

  • Current medical or psychological illness
  • Use of antidepressants, antianxiolytics, or compounds that alter cerebral blood flow
  • Claustrophobia
  • Pregnancy

Investigators

Study Sites (1)

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