Outcomes' Predictors in Post-Surgery Extracorporeal Life Support
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Cardiogenic Shock
- Sponsor
- University of Florence
- Enrollment
- 500
- Locations
- 1
- Primary Endpoint
- Survival
- Status
- Recruiting
- Last Updated
- 5 years ago
Overview
Brief Summary
Extracorporeal Life Support (ECLS) may provide pulmonary and circulatory support for patients with acute heart failure refractory to conventional medical therapy. However, indications and effectiveness of ECLS engagement post-surgery remains a concern. The investigators sought to analyze indications, modality and outcomes of PS-ECLS, to identify predictors of early and midterm survival after PS-ECLS. The investigators have recorded prospectively, and analysed data of 209 consecutive PS-ECLS patients between January 2004 and December 2018. Demographic and clinical data before, during and after PS-ECLS were collected and their influence on hospital mortality and outcomes (early and midterm) will analyse. Multivariate analysis of pre PS-ECLS implantation factors (as age, female sex , insulin-dependent diabetes, pulmonary hypertension, STS, type of surgical procedure data, pre-ECLS blood lactate level) will be made for identify prognostic risk factors of in-hospital mortality. Overall survival will be analysed, at 6 months,1-year and 5-years, respectively and the factors influencing mild/term outcome will be investigated.
Investigators
Massimo Bonacchi
Professor
University of Florence
Eligibility Criteria
Inclusion Criteria
- •Patients underwent cardiac surgery
Exclusion Criteria
- •Age \< 18 years
Outcomes
Primary Outcomes
Survival
Time Frame: At 5 years after surgery
late survival
Secondary Outcomes
- Prognostic Factors(Late: 5 years after surgery)
- Prognostic factors(Early: 1 month after surgery)