Skip to main content
Clinical Trials/NCT04316078
NCT04316078
Completed
Not Applicable

A Novel Patient Engagement Platform Used to Improve Understanding, Treatment Compliance and Quality of Care Among Patients With Gastrointestinal Malignancies

Sheba Medical Center1 site in 1 country126 target enrollmentMarch 15, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Colon Cancer
Sponsor
Sheba Medical Center
Enrollment
126
Locations
1
Primary Endpoint
Feasibility of PEP (percent of patients using videos/complete questionnaires)
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

A randomized control trial to evaluate the feasibility of implementing a patient educational platform (PEP) for patients with gastrointestinal malignancies undergoing active chemotherapy treatment.

Detailed Description

Patients will be randomized in a 2:1 ratio. Patients in the experimental arm will receive automatically generated personalized educational videos (PEV) and questionnaires regarding side effects and quality of life (QOL) to either their cell phone or email. The videos will be personalized to each patient based on their demographics, specific medical instructions and treatment plan. Data collected regarding side effects and QOL in the experimental arm will be used in order to facilitate real time intervention through real time provider alert system. A link to the first PEV will be sent before the first chemotherapy cycle, addressing the diagnosis and type of malignancy, chemotherapy protocol, common side effects and their management. Side effects questionnaire will be sent every week while QOL questionnaire will be sent every 6 weeks. Patients will be followed from recruitment through three weeks after completion of the planned treatment protocol. If treatment is discontinued prior to completion of the protocol, follow-up will end three weeks after the last administered treatment.

Registry
clinicaltrials.gov
Start Date
March 15, 2020
End Date
April 15, 2022
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Individuals with a newly diagnosed gastrointestinal malignancy, treated at the outpatient clinic of the Institute of Oncology at the Sheba Medical Center
  • Individuals planned to receive one of the following cytotoxic chemotherapy protocols:
  • FOLFOX - a combination of 5-fluoruracil, leucovorin and oxaliplatin.
  • FOLFOIRI - a combination of 5-fluoruracil, leucovorin and irinotecan.
  • FOLFIRINOX - a combination of 5-fluoruracil, leucovorin, oxaliplatin and irinotecan.
  • De Gramont - 5-fluoruracil and leucovorin.
  • Ability to read and comprehend Hebrew language text.
  • Ability to see computer or cell phone screen (i.e., no visual impairment).

Exclusion Criteria

  • Eastern Conference Oncology Group (ECOG) performance status greater than
  • Cognitive deficits that would preclude understanding of consent form and/or questionnaires.
  • Inability to read and comprehend Hebrew language text.
  • Current participation in a therapeutic clinical trial.

Outcomes

Primary Outcomes

Feasibility of PEP (percent of patients using videos/complete questionnaires)

Time Frame: 3 years

To assess the feasibility of implementing a PEP in the outpatient gastrointestinal malignancies service, at Sheba Medical Center, for patients undergoing active chemotherapy treatment. This outcome will be measured as percent of patients using the videos and percent of patients that complete the questionnaires.

Secondary Outcomes

  • Secondary clinical outcomes 1 (mean number of referrals)(3 years)
  • Secondary clinical outcomes 2 (level of chemotoxicity)(3 years)
  • Secondary clinical outcomes 3 (Quality of Life)(3 years)
  • Secondary clinical outcomes 4 (treatment intensity and continuity)(3 years)

Study Sites (1)

Loading locations...

Similar Trials