A Randomized Controlled Study of Acupuncture Intervention for Subthreshold Depressio
- Conditions
- Subthreshold Depression
- Registration Number
- ITMCTR2100005147
- Lead Sponsor
- Affiliated Hospital of Shandong University of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
1. Meet the diagnostic criteria for subthreshold depression;
2. Aged between 18-60 years, and the gender is not limited;
3. Hamilton-17-item Depression Scale (HAMD-17) score: 7 points <= HAMD <17 points;
4. Have not used any antidepressant drugs for at least 2 weeks before treatment, and have not received acupuncture treatment for depression in the past 3 months;
5. It is forbidden to take antibiotics, probiotics and fermented dairy products such as yogurt before entering the group and providing specimens;
6. Be able to actively cooperate with the treatment and sign the informed consent.
1. Patients with clinically diagnosed depression, previous mental illness or organic mental disorder;
2. Those with severe liver and kidney damage, severe arrhythmia or cardiac insufficiency;
3. Pregnant and lactating patients;
4. Depressive episodes caused by psychoactive substances or non-addictive substances;
5. The patient has a strong suicide attempt or behavior;
6. Those who cannot tolerate acupuncture treatment;
7. Those who have communication difficulties or do not cooperate with the researcher;
8. Other situations judged by the investigator to be inappropriate for inclusion in the observation.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hamilton depression scale;
- Secondary Outcome Measures
Name Time Method Generalized anxiety scale;The proportion of people who developed moderate depression;9 items of patient health questionnaire;Quality of life scale SF12 2nd edition;