Caffeine treatment for stimulation of spontaneous breathing in preterm infants at birth

Completed

• Conditions: improvement of breathing of neonates; Respiratory function due to caffeine treatment; 10028971

• Registration Number: NL-OMON41183
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 26

Inclusion Criteria

Preterm infants born <30 weeks GA.

Exclusion Criteria

Congenital abnormalities or condition that might have an adverse effect on breathing or ventilation, including: congenital diaphragmatic hernia, trachea-esophageal fistula or cyanotic heart disease.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>- Average respiratory minute volume at 7-10 minutes after birth</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- Average Rate of rise to maximum tidal volume at 7-10 minutes after birth<br /><br>- Time of mask ventilation given<br /><br>- Oxygen saturation and heart rate in the first 10 minutes from birth<br /><br>- Maximal oxygen needed in the first 10 minutes<br /><br>- Total amount of pure oxygen given to the patient (oxygen load) will be<br /><br>calculated taking into consideration birth weight, tidal volume, respiratory<br /><br>rate, fraction of inspired oxygen and timing of stabilisation</p><br>