Comparative study between caudal Dexmedetomidine and Morphine

Recruiting

• Conditions: Pediatric patients undergoing lower abdominal surgeries under General Anaesthesia

• Registration Number: CTRI/2017/03/008245
• Lead Sponsor: Armed forces Medical College Pune

Brief Summary

Caudal epidural blocks are the most commonly used technique providing intra and postoperative analgesia in pediatric lower abdominal surgeries. Caudal  anlgesia proved to be simple and effective technique.Inspite of using long acting local anaesthetics, the main disadvantage of caudal analgesia remains the relatively short duration of action.The practice of adding adjunct analgesic drugs to local anesthetics for caudal block is common.  Clinically, the addition of both morphine and dexmedetomidine prolongs the duration of caudal analgesia. Aim of the study is to compare the analgesic effects of  Dexmedetomidine and morphine  as  adjuncts  to Bupivacaine in caudal block.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-04-15
• Last Update Posted: 2017-03-28

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• ASA physical status I and II 2.
• Pediatric patients between 2-10 yeras undergoing lower abdominal surgeries 3.
• Written informed parental consent 4.
• Elective surgery.

Exclusion Criteria

• Known allergy to study drugs 2.
• History of developmental delay or mental retardation 3.
• Patients with coagulopathies 4.
• Signs of infection at the site of caudal block 5.
• Skeletal deformities in the caudal region 6.
• Patient or parental refusal 6.
• Neurological disorder or deficit.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the post operative analgesia produced by Dexmeditomidine and Morphine when used as additive to bupivacaine (using FLACC pain scale with 0-10 score range)	In post anesthesia care unit and every 2 Hourly

Secondary Outcome Measures

Name	Time	Method
To compare the post operative sedation when Dexmedetomidine and Morphine used as adjuncts to Bupivacaine in caudal block(using modified Ramsay Sedation Scale)	In Post Anaesthesia Care Unit and every 4 hrly

Trial Locations

Locations (1)

OT COMPLEX, DEPARTMENT OF ANAESTHESIOLOGY AND CRITICAL CARE; 🇮🇳 Pune, MAHARASHTRA, India

OT COMPLEX, DEPARTMENT OF ANAESTHESIOLOGY AND CRITICAL CARE

🇮🇳Pune, MAHARASHTRA, India

Lt Col Amit Rai

Principal investigator

08411052137

drraiamit@gmail.com