Degree of habitual behaviour modulation of non-invasive brain stimulation effects on cognitive flexibility in healthy participants.

Not Applicable

Recruiting

• Conditions: earning; Learning; Mental Health - Studies of normal psychology, cognitive function and behaviour

• Registration Number: ACTRN12622000871741
• Lead Sponsor: Murdoch University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-06-20
• Last Update Posted: 27 June 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

•You are aged between 18 and 50 years (the upper age limit of 50 years has been selected as there is some evidence that mild cognitive decline begins past this age)
•You are in good health
•You agree to fast 3 hours prior to testing (only water or herbal tea allowed) (glucose levels are known to modulate performance in several cognitive domains. By having all participants fast for 3 hours prior to testing, we can rule out an enhancing effect of glucose on the cognitive flexibility task).

Exclusion Criteria

Participants will not be able to participate if they:
•Suffer from cardiac, hepatic, renal, and/or neurological disorders
•Have damaged or diseased skin on your face and scalp, or a sensitive scalp
•Have a history of alcohol or drug addiction, or severe psychiatric illness
•Are receiving drug treatment which may lower seizure threshold (i.e. epilepsy)
•Are pregnant
•Are sleep deprived (less than 6 hours a day)
•Have metallic dental fillings, orthodontic appliances, a cardiac pacemaker, cochlear
implant, and/or surgical clips

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Total errors in the Wisconsin Card Sorting task[Immediately before tDCS (sham or cathodal) and 10 minutes following tDCS activation across two experimental sessions.];Perseverative errors in Wisconsin Card Sorting Test[Immediately before tDCS (sham or cathodal) and 10 minutes following tDCS activation across two experimental sessions.];Reaction times in the Wisconsin Card Sorting task[Immediately before tDCS (sham or cathodal) and 10 minutes following tDCS activation across two experimental sessions.]

Secondary Outcome Measures

Name	Time	Method
Failure to maintain set in the Wisconsin Card Sorting task[Immediately before tDCS (sham or cathodal) and 10 minutes following tDCS activation across two experimental sessions.]