NL-OMON36638RecruitingNot Applicable
(f)MRI parameters and the relation with cognitive and emotional dysfunction in patients after treatment for M. Cushing and a comparison with patients with anxiety and depression - (f)MRI in Cushing's disease
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Enrollment
- 50
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 18 to 99 (—)
Inclusion Criteria
- •- men and women between 18 and 55 years of age
- •- patients treated for M. Cushing by transsphenoidal surgery with or without additional radiotherapy
- •- adequately substituted
- •- patients should be prepared and well informed about the study
- •- patients should sign the informed consent
Exclusion Criteria
- •- difficulty to understand the Dutch language
- •- history of contusio cerebri
- •- presence of non-endocrinological impairments which could influence brainstructure or function
- •- chronic misuse of alcohol or drugs
- •- medication (other than suppletion) that could influence perfusion or cognition and can not be stopped two days before the scan takes place, with exclusion of SSRI in stable dossage
- •- contraindications for MRI, such as metal implants, heart arrhythmia, claustrophobia etc.
Investigators
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