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Clinical Trials/NL-OMON36638
NL-OMON36638
Recruiting
Not Applicable

(f)MRI parameters and the relation with cognitive and emotional dysfunction in patients after treatment for M. Cushing and a comparison with patients with anxiety and depression - (f)MRI in Cushing's disease

eids Universitair Medisch Centrum0 sites50 target enrollmentTBD
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ConditionsCushing's diseasehypercortisolism10021112

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cushing's disease
Sponsor
eids Universitair Medisch Centrum
Enrollment
50
Status
Recruiting
Last Updated
last year
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
last year
Study Type
Observational non invasive

Investigators

Eligibility Criteria

Inclusion Criteria

  • •\- men and women between 18 and 55 years of age
  • •\- patients treated for M. Cushing by transsphenoidal surgery with or without additional radiotherapy
  • •\- adequately substituted
  • •\- patients should be prepared and well informed about the study
  • •\- patients should sign the informed consent

Exclusion Criteria

  • •\- difficulty to understand the Dutch language
  • •\- history of contusio cerebri
  • •\- presence of non\-endocrinological impairments which could influence brainstructure or function
  • •\- chronic misuse of alcohol or drugs
  • •\- medication (other than suppletion) that could influence perfusion or cognition and can not be stopped two days before the scan takes place, with exclusion of SSRI in stable dossage
  • •\- contraindications for MRI, such as metal implants, heart arrhythmia, claustrophobia etc.

Outcomes

Primary Outcomes

Not specified

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