(f)MRI parameters and the relation with cognitive and emotional dysfunction in patients after treatment for M. Cushing and a comparison with patients with anxiety and depressio
- Conditions
- Cushing's diseasehypercortisolism10021112
- Registration Number
- NL-OMON36638
- Lead Sponsor
- eids Universitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 50
- men and women between 18 and 55 years of age
- patients treated for M. Cushing by transsphenoidal surgery with or without additional radiotherapy
- adequately substituted
- patients should be prepared and well informed about the study
- patients should sign the informed consent
- difficulty to understand the Dutch language
- history of contusio cerebri
- presence of non-endocrinological impairments which could influence brainstructure or function
- chronic misuse of alcohol or drugs
- medication (other than suppletion) that could influence perfusion or cognition and can not be stopped two days before the scan takes place, with exclusion of SSRI in stable dossage
- contraindications for MRI, such as metal implants, heart arrhythmia, claustrophobia etc.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method