Is low intensity resistance training combined with blood flow restriction beneficial to the rehabilitation of patients with knee osteoarthritis?

Not Applicable

Completed

• Conditions: Female patients with unilateral knee osteoarthritis; Musculoskeletal Diseases

• Registration Number: ISRCTN51633853
• Lead Sponsor: Qingdao Haici Hospital

Brief Summary

2022 Results article in https://pubmed.ncbi.nlm.nih.gov/36281415/ (added 09/07/2024)

Detailed Description

Not available

Study Timeline

• Study Start: 2022-05-16
• Study Completion: 2022-07-25
• Last Update Posted: 22 July 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 18

Inclusion Criteria

1. Currently experiencing objective functional limitations
2. Female aged between 40 and 70 years old
3. Symptomatic unilateral knee OA
4. Not participating in any regular resistance training.

Exclusion Criteria

1. Health status contradicted the use of a tourniquet
2. Currently suffering from peripheral vascular disorders or any condition contradicting subjecting them to exercise training
3. High blood pressure defined by a diastolic blood pressure >100 mm Hg or resting systolic blood pressure >160 or <100 mm Hg

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Blood lactate (BLA), IGF-1, GH and testosterone levels will be tested at 4-time points using blood test: before exercise, immediately after exercise, 15 minutes after exercise, and 30 minutes after exercise.

Secondary Outcome Measures

Name	Time	Method
Heart rate measured using heart rate band during exercise