Role of oral dextromethorphan in relieving cough during flexible bronchoscopy
Phase 4
- Conditions
- Health Condition 1: J40- Bronchitis, not specified as acuteor chronic
- Registration Number
- CTRI/2020/06/026115
- Lead Sponsor
- Manoj Kumar Panigrahi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients aged >=18 years and <=70 years who required diagnostic bronchoscopy for any valid indication
Exclusion Criteria
a.Lack of informed consent.
b.Profound refractory hypoxemia.
c.Severe bleeding diathesis.
d.Recent myocardial infarction or unstable angina.
e.Respiratory failure.
f.Uncontrolled hypertension.
g.Unstable cardiac arrhythmias.
h.Pregnant or lactating women.
i.Renal failure.
j.Use of sedatives or centrally acting drugs 12 hours
prior to bronchoscopy.
k.Patient taking Monoamine Oxidase inhibitors or
serotonergic agents.
l.History of hypersensitivity to dextromethorphan
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method A.To assess the effect of oral dextromethorphan premedication on severity of cough during bronchoscopyTimepoint: 0 and 1 hour
- Secondary Outcome Measures
Name Time Method 1.To evaluate the impact of dextromethorphan premedication on requirement of sedative used during flexible bronchoscopy <br/ ><br>2.To assess the effect of dextromethorphan premedication on quantity of topical anaesthetics used during the procedure. <br/ ><br>Timepoint: 0 hour