Biological Consequences of an Ultra Endurance Race

• Conditions: Exertion; Excess

• Registration Number: NCT03194022
• Lead Sponsor: Hôpital Necker-Enfants Malades

Brief Summary

The aim is to study per and post-exertion variations of biological markers during an ultra-endurance race

Detailed Description

25 healthy adult volunteers participating in the "100 miles South of France 2017©" race recruited electronically by an announcement on the race website

Study Timeline

• Study First Submitted: 2017-06-16
• Study First Submitted QC: 2017-06-19
• Study First Posted: 2017-06-21
• Status Verified: 2018-08
• Last Update Submitted: 2018-08-01
• Last Update Posted: 2018-08-03
• Study Start: 2018-10-01
• Primary Completion: 2018-10-01
• Study Completion: 2018-10-17

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Male
• Target Recruitment: 25

Inclusion Criteria

1. Age greater 18 years.
2. Subject having already completed an ultra-endurance race (distance greater than 50 kilometers) during the 24 months preceding the race.
3. Affiliation of a social security.

Exclusion Criteria

1. Age lower than 18 years
2. Subjects with a medical history (pulmonary pathology, cardiac, hypertension) or having a significant chronic inflammatory disease known at the time of the inclusion visit the day before the race.
3. Female

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Per and post-exertion evolution of sodium blood level	Change measures : departure, 15, 50, 65, 90, 130 and 165 kilometers then at day 1 and 2 after the completion of the race	Change of sodium blood level during and after the race will be measured.
Per and post-exertion evolution of potassium blood level	Change measures : departure, 15, 50, 65, 90, 130 and 165 kilometers then at day 1 and 2 after the completion of the race	Change of potassium blood level during and after the race will be measured.
Per and post-exertion evolution of lactatemia	Change measures : departure, 15, 50, 65, 90, 130 and 165 kilometers then at day 1 and 2 after the completion of the race	Change of lactatemia during and after the race will be measured.
Per and post-exertion evolution of myoglobin blood level	Change measures : departure, 15, 50, 65, 90, 130 and 165 kilometers then at day 1 and 2 after the completion of the race	Change of myoglobin blood level will be measured during and after the race
Per and post-exertion evolution of creatinine phosphokinase blood level	Change measures : departure, 15, 50, 65, 90, 130 and 165 kilometers then at day 1 and 2 after the completion of the race	Change of myoglobin blood level will be measured during and after the race
Per and post-exertion evolution of chlorine blood level	Change measures : departure, 15, 50, 65, 90, 130 and 165 kilometers then at day 1 and 2 after the completion of the race	Change of chlorine blood level during and after the race will be measured.
Per and post-exertion evolution of calcium blood level	Change measures : departure, 15, 50, 65, 90, 130 and 165 kilometers then at day 1 and 2 after the completion of the race	Change of calcium blood level during and after the race will be measured.
Per and post-exertion evolution of glucose blood level	Change measures : departure, 15, 50, 65, 90, 130 and 165 kilometers then at day 1 and 2 after the completion of the race	Change of glucose blood level during and after the race will be measured.